Bioinformatics

From the Biology department and in cooperation with Boston University. Emphasis on the ability to integrate knowledge from biological, computational, and mathematical disciplines.

Specializes in epitope prediction and protein analysis for proteomics, diagnostics, therapeutics, life science research, and antibody production.

Explores and designs metabolic pathways.

Provides scientists in pharmaceutical and biotechnology research tools to optimize the mining, analysis and management of life science data.

Developer of bioinformatics software to parse and display microarray data.

Provider of customized bioinformatics tools and services. Existing portfolio includes protein annotation tools, metagenomics integration systems, drug and protein interaction analysis tools.

Develops software for bioinformatics and genomics including aligners for single ended and paired end reads from the Illumina Genome Analyser.

Develops and applies computational and statistical methods to detecting and characterizing genetic, genomic, and proteomic biomarkers of common human diseases.

Bioinformatics research center with over 100 scientists with biological, physical and computational expertise engaged in interdisciplinary research.

Freeware DNA cloning, analysis and visualization software.

A graphical user interface for linear modelling of cDNA and oligonucleotide microarray data to identify differentially expressed genes.

A sequence assembly suite with SNP detection for "hard" projects.

Offers CodonCode Aligner, a DNA sequence assembly, sequence alignment, contig editing and mutation detection software for Windows and Mac OS X.

An integrated database of genomic, expression and protein data for Drosophila and Anopheles.

A transcriptome-wide atlas database for the developing mouse embryo established by RNA in situ hybridization.

A multiple-sequence alignment program that also includes distance matrix methods for inferring trees.

A database built from Pfam, PRINTS and PROSITE.

Secondary protein structure prediction from amino acid sequence; based on a consensus from several methods including DSC, PHD, NNSSP, PREDATOR, ZPRED, and MULPRED.

Identifies functionally important regions on the surface of a protein or domain, of known three-dimensional (3D) structure using the phylogenetic relations between close sequence homologues.

Service for detecting the multiple structural alignments of proteins. Uses the common geometrical cores between the input molecules. Does not require that all the input molecules participate in the alignment.

A compilation of transcriptional regulatory protein factors and their cognate gene promoter elements along with DNA sequence search and analysis programs - from GBF, Braunschweig, Germany.

Integrated resource, which provides information about ligands, sequence and structure motifs, their relative position and the neighbour environment.

Provides drug discovery using computational technology to simulates intermolecular interactions.

Business, science and technology consulting services to biotechnology and pharmaceutical companies that utilize genomic and proteomic based drug discovery.

Offer biomedical research tools, database and outsourcing implementations of sequence analysis for informatics projects. Includes publications and conatcs in Houston, Texas.

The Bioconductor project produces an open source software framework that will assist biologists and statisticians working in bioinformatics, with primary emphasis on inference using DNA microarrays, built mostly using R.

BioSharp is an open-source project to provide a framework for processing biological data using C# and other .net languages.